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Reply To: Is the alcohol warning with metronidazole real?

northwindow 2 weeks ago

Your friend is closer to the evidence than the leaflet is. The supposed disulfiram like reaction with metronidazole has been looked at repeatedly and the evidence for it is thin. A small controlled study found no reaction and no change in the enzyme the theory depends on.

The warning stayed in the labelling anyway, which is why you were told it firmly.

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